Having trouble writing an essay
Tuesday, August 25, 2020
SWOT Analysys Coursework Example | Topics and Well Written Essays - 1000 words
SWOT Analysys - Coursework Example The incredible development of the association is showed in expanding the extent of tasks into in excess of 220 nations worldwide with 300,000 representatives working through four explicitly characterized lines of activities: express, cargo sending, gracefully chain and mail. In 2002, DHL was united and claimed by Deutche Post World Net yet held the well known corporate and brand name. The mission of DHL is to give phenomenal client assistance in the field of global express vehicle and coordinations and to accomplish is objective of being the coordinations organization of the world (DHL: Strategy, 2011, standard. 2). The executives endeavors to accomplish this strategic following with severe measures of value and moral duty of safeguarding and securing the earth as they use different assets successfully and effectively. II. Hierarchical Strengths and Weaknesses A. Capable Leadership and Managerial Expertise One of the qualities of DHL is its pool of capable, qualified and various pion eers who are considered specialists in their individual fields of attempt. This is a particular ability in light of the fact that as it works in different pieces of the world, solid administration drive and possibilities are sharpened through different impetuses and systems that advance ââ¬Å"self-activity among our representatives through such exercises as thought the board, reward singular execution and join extraordinary significance to solidarity. The First Choice Program, a basic mainstay of our development procedure, is intended to accomplish methodical execution enhancements at the interface with the customerâ⬠(DHL: The Group, 2011, standard. 1). By rousing, creating and keeping up its differing pool of staff, their abilities are adequately tackled towards accomplishment of its corporate crucial objectives. B. The Ability to Steer Growth in Strategic Locations DHL had been fruitful in distinguishing vital areas around to world to extend its procedure on a worldwide sca le. The investigation led by FAI Consulting Services (2009) uncovered that ââ¬Å"the organization has utilized cross-useful groups the world over to plan, structure, and oversee facilitiesâ⬠(standard. 4). In a range of 4 decades, the quantity of worldwide accomplices drastically expanded by improving ââ¬Å"its aptitude by buying other driving coordinations organizations, for example 1999 procurement of Danzas, 2004/2005 obtaining of 88 percent of portions of Indian express organization Blue Dart, end of 2005 securing of Exelâ⬠(DHL: Facts and Figures, 2010, standard. 6). C. Propensity for Complacency An investigation composed by Apostolopoulos, et.al. (1998) demonstrated that there is a prominent shortcoming confronting corporate workers as they show inclinations for carelessness. The method of reasoning for this is the market administration unmistakably picked up by DHL throughout the years. The model workplace concurred faculty work fulfillment level that gave them be nefits they esteemed were more than anticipated and in this way ought not be tested nor disturbed. The association can limit this shortcoming through additionally testing execution assessment and examination programs that measure their work disposition and apply fitting arrangements of remunerations and punishments as esteemed vital. 2. Examine how the association can limit this shortcoming. D. Announced Poor Customer Service In locales that uncover client grievances, DHL clients were protesting the poor client support showed
Saturday, August 22, 2020
World War Is Mitteleuropa
Universal War I's Mitteleuropa German for ââ¬ËMiddle Europeââ¬â¢, there are a wide scope of translations for Mitteleuropa, yet boss among them was the German arrangement for a realm in focal and eastern Europe that would have been made had Germany won the First World War. War Aims In September 1914, a couple of months after the beginning of World War I, German Chancellor Bethmann Hollweg made the ââ¬ËSeptember Programmeââ¬â¢ which, alongside different archives, set out a bombastic arrangement for post-war Europe. It would be ordered if Germany was absolutely fruitful in the war, and by then nothing was sure. A framework called ââ¬ËMitteleuropaââ¬â¢ would be made, a financial and customs association of focal European grounds that would be driven by Germany (and to a lesser degree Austria-Hungary). Just as these two, Mitteleuropa would incorporate German mastery of Luxembourg, Belgium and their Channel Ports, the Baltic and Poland from Russia, and perhaps France. There would be a sister body, Mittelafrika, in Africa, prompting German authority of the two landmasses. That these war points must be developed after the war began is regularly utilized as a stick with which to beat the German order: they are predominantly accused for beginning the war and didnââ¬â¢t even recognize what they needed past having dangers from Russia and France expelled. Itââ¬â¢s muddled precisely how far the German individuals bolstered this fantasy, or how genuinely it was taken. For sure, the arrangement itself was permitted to blur as it became evident the war would keep going quite a while and may not be won by Germany by any means. A variety rose in 1915 when the Central Powers vanquished Serbia and Germany proposed a Central European Federation be made, driven by Germany, this time perceiving the requirements of the war by setting every single military power under German order. Austria-Hungary was as yet sufficiently able to protest and the arrangement again blurred. Insatiability or Matching Others? For what reason did Germany focus on a Mitteleuropa? To Germanyââ¬â¢s west were Britain and France, a couple of nations with a huge worldwide domain. Toward the east was Russia, which had a land realm extending to the Pacific. Germany was another nationâ and had passed up a great opportunity as the remainder of Europe had cut the world up between them. Be that as it may, Germany was an eager nationâ and needed a realm as well. At the point when they checked out them, they had the immensely amazing France straightforwardly west, however among Germany and Russia were eastern European expresses that could shape a realm. English language writing racistly viewed as an European triumph as more regrettable than their own worldwide victories, and painted Mitteleuropa as altogether more awful. Germany had activated a large number of individuals and endured a great many losses; they attempted to concoct war intends to match.In the end, we donââ¬â¢t know how far Mitteleuropa would have been made. It was thought up in a snapshot of turmoil and activity, yet maybe the Treaty of Brest-Litovsk with Russia in March 1918 is a hint, as this moved a tremendous zone of Eastern Europe to German control. It was their disappointment in the west that made this baby domain be deleted.
Sunday, July 26, 2020
Columbia Dual Degree When do I apply COLUMBIA UNIVERSITY - SIPA Admissions Blog
Columbia Dual Degree When do I apply COLUMBIA UNIVERSITY - SIPA Admissions Blog A question our office commonly receives is, I am interested in applying to a dual degree program with SIPA and another Columbia school. When do most applicants apply to dual degree programs at Columbia? The rule at Columbia is that you must be admitted into a dual degree program no later than half way through your first degree. For most students this means that they must apply no later than the completion of the first semester of study. For example, the program at SIPA is a two-year program. If someone who started at SIPA wished to apply for a dual degree with another school, the application to the dual degree school would need to be completed roughly around the end of the first semester at SIPA. Most programs have an application deadline sometime in the months between December and February. Thus, if someone completed their first year at SIPA, it would be too late to apply for a dual degree with another school. Because of the tight time line, our recommendation is that if an applicant knows they are interested in a dual degree program with another Columbia school, it is wise to apply to both programs at the same time. This will require that an application be submitted to each school separately and there is no joint committee that reviews applications. The Admissions Committee at each school will make an independent decision. If admitted to both schools the applicant can choose where they would like to begin. For a list of dual degree programs, please click here.
Friday, May 22, 2020
Domestic Violence Is Not Only About Using Physical Force
I. Introduction Domestic violence is considered a crime in the United States and in many other countries around the world. Every 15 seconds, there is a woman being beaten by her husband or intimate partner. When we think of domestic violence, our minds automatically create an image of a male physically abusing a female. Although in most cases the victim is usually a female, we must also be aware that in todayââ¬â¢s society, men are also victims of domestic violence. According to the Bureau of Justice Statistics Crime Data Brief, about 3.2 million men are abused by their partners each year (Domestic). However, this is only an estimate based on reported incidents. It is also extremely important to understand that domestic violence, is not onlyâ⬠¦show more contentâ⬠¦Although, forensic psychology was founded decades ago, it still remains as one of the more recent branches of psychology. The contribution of a forensic psychologist plays a critical role in the process of many crime investigatio ns. The most important task of a forensic psychologist is conducting psychological assessments of any suspect involved in a crime case, including children. For that reason, a forensic psychologist must have a strong foundation of both clinical skills and law training (Ward, 2013). III. Battered Woman Syndrome One of the most common defense arguments used in domestic violence homicide crimes, is the act of self-defense due to battered woman syndrome (BWS). Battered woman syndrome is a theory that was developed by clinical psychologist, Dr. Lenore Walker during the 1970ââ¬â¢s. Her approach towards BWS explains why battered women kill their abusive partners, instead of ending the relationship. According to Dr. Walker, many victims of domestic violence find it difficult to end an abusive relationship due to ââ¬Å"learned helplessnessâ⬠(Rodgers, 2017). Dr. Walker also discovered that most women with BWS follow a pattern called ââ¬Å"The Cycle of Violenceâ⬠. She explains that the cycle consists of three different stages: The tension building stage, the acute battering incident stage and the honeymoon stage. In the first stage, victims cover up for the partnerââ¬â¢s abuse toward family and friends. This leadsShow MoreRelatedViolence is the Physical Force Prohibited by Law799 Words à |à 3 Pagesââ¬Å"Violenceâ⬠¦the unlawful exercise of physical forceâ⬠(The Concise Oxford English Dictionary). How Well Does This Statement Define Interpersonal Violence? One of the most common ways of defining violence is to only consider forms of criminal violence and to argue that violence is the use of force that has been prohibited by law (Riedel Welsh, 2002, p.3). The Oxford dictionary when taking a legal dimension, defines violence as ââ¬Å"the unlawful exercise of physical forceâ⬠. This definition suggestsRead MoreSpeech on Domestic Violence - Urban Issue986 Words à |à 4 PagesSpeech for Urban Issue ââ¬â Domestic Violence Domestic Violence is violence or physical abuse directed toward your spouse or partner, usually its violence by men against women Domestic Violence or DV is about power and control over a spouse. The three main types of Domestic Violence are Physical, Emotional, and Economic (financial) The first kind of domestic violence that we will be talking about is physical violence. Physical violence involves a person using physical force which causes harm to spouseRead MoreA Research On Domestic Violence1697 Words à |à 7 PagesResearch Paper Development Log Domestic Violence. Domestic violence is defined like an action by one person against another with the intent to cause harm and tried to getting power and control over the other. (Psychology Dictionary) For me there s no better definition of domestic violence than the one that was previously stated, since it involves two keywords: harm and power. (Retrieved from http://www.chicagojustice.org/research/long-form-reports/violence-againt-women-in-the-news/Chart%20C%20SA%20Race-Ethnicity%20of%20OffendersRead More We Must Work Together to Reduce Domestic Violence1303 Words à |à 6 Pages Domestic violence is an act of crime which occurs in domestic household units. It is also known as as spousal abuse or family violence. Domestic violence is not only related to physical abuse but also emotional, sexual, financial, mental and verbal threats. According to ( Human Right Watch, 1995) cited from Macionis, John J., 2008. Domestic violence is defined as bodily harm, usually accompanied by verbal threats and harassment, emotional abuse or the destruction of property as meansRead MoreDomestic Violence868 Words à |à 4 PagesINFORMATIVE SPEECH: ââ¬Å"What is domestic Violence, how common it is and which are some of the main signs that we can recognize domestic relationships.â⬠ââ¬Å"What do you think that is Domestic Violence?â⬠Before I answer to this question, let me tell you a short story. Her friends describe Maria ââ¬Å"as the perfect girlâ⬠. She is beautiful, she is working and she has many friends. However, Maria has many problems in her family. Her father is alcoholic and he is not working to feet his family. So,Read MoreWhat is Domestic Violence? Essays1749 Words à |à 7 PagesDomestic Violence Domestic violence is a pattern of physical and mental abuse and controlling behavior in a relationship and can happen to anyone, regardless of age, race, sexual orientation, religion, or gender; this type of abuse can have both short and long term affects and can cause physical, mental, and emotional pain. While abuse can happen to anyone, women are by far the most frequent victims and men are the most frequent abusers. The U.S. department of justice estimates that 95 percent ofRead MoreDomestic Violence And Its Effects On Women1599 Words à |à 7 PagesDomestic violence is a large social issue around the world that is commonly associated with the mistreatment of women. However, there are many different forms of domestic violence that affect men, women, and children (Domestic Violence 1). Victims of domestic violence may suffer not only physically, but emotionally and mentally as well. Domestic violence is a very important social issue because it negatively affects both the abuser a nd the victim. In the article, ââ¬Å"Domestic Violence and Abuse: TypesRead MoreA Thousand Splendid Suns : Domestic Violence Essay1403 Words à |à 6 PagesOctober 2016 A Thousand Splendid Suns Social Issue: Domestic Violence Domestic violence is an act of violence or abuse against a person living in oneââ¬â¢s household, especially a member of oneââ¬â¢s immediate family. It includes physical violence, sexual violence, threats, and emotional abuse. The frequency and severity of domestic violence can vary dramatically. Statistical/ Demographical Information About Domestic Violence: â⬠¢85% of domestic violence victims are women â⬠¢1 in 3 women and 1 in 4 men inRead MoreThe Use Of Force And Gender Symmetry1493 Words à |à 6 Pagess use force is often in self-defense, retaliation, or to express anger, stress or frustration, whereas men s use of violence is often to control and exercise power over their partners. Thus, the motivation for violence differs between men and women. Furthermore, the damage caused by women when using force does not equal to that caused by men. Therefore, gender symmetry does not exist in domestic violence. Main Findings Use of Force and Gender Symmetry Gender symmetry in terms of domestic or intimateRead More Domestic Violence Essay with Annotated Bibliography1593 Words à |à 7 Pagesdifferent types of domestic violence. Physical abuse is the most obvious form, but this is not to say that outsiders always recognize it. Generally, physical violence causes bodily harm, using a variety of methods. Slapping, pushing, throwing, hitting, punching, and strangling are only a few methods. An object or weapon may or may not be used. There is not always physical evidence of physical abuse such as bruising, bleeding, scratches, bumps, etc., therefore, absence of physical marks does not necessarily
Friday, May 8, 2020
Essay about A Career in Mental Health Nursing - 1383 Words
What is it that makes choosing a career so difficult? Is it the fact that many people mainly choose a career they live off for the rest of their lives? Or is it just that they are scared of the difficulties and obstacles that will come through their path? Many students choose the usual careers: nursing, doctors, mechanics, or just working at a gas station. It all depends on where and if the student decides to go to college and what degree they are looking forward to earning. Becoming a mental health nurse would be a good choice because it pays very well. Students are recommended to go to college and get their Bachelors and Mastersââ¬â¢ degree. It will take a lot of studies but it will be worth it. ââ¬Å"Most of us take our mental health forâ⬠¦show more contentâ⬠¦Ã¢â¬Å"Mental health nurse also work with families of patients to make sure that patients are getting all the help that they can. In addition, they may play a roll in educating the community about mental health issues.â⬠(Career Cruising) Depending on what they choose, mental health nurses can help either children or the elder. Many work with those who are a danger to themselves and others. ââ¬Å"Some mental health nurses are trained and assigned to work within the prison populations. Some may work with those who have substances abuse problems.â⬠Mental health nurses work in many areas such as, hospitals, clinics, schools, prisons, and some government agencies. Depending on the nursesââ¬â¢ shifts, some who work full time work a total of forty hours a week. Nurses who work in clinics or hospitals have rotating shifts, meaning evenings and weekends. During the ââ¬Å"studentâ⬠stage of nursing need to be able to understand the patients origins. A disadvantage to this job would be, depending on whom nurses work with, this job can become stressful. The patients the nurses work with can be emotional in several ways including being aggressive. Traveling to the patients house may be required and other various community sites. It is highly recommended to take certain courses in high school if you are interested in the health care field. Depending on the employer, education requirements vary. ââ¬Å"However, at the minimum you must first become a registered nurse by earning aShow MoreRelatedThe Global Issue Of Mental Health And Shortage Of Nursing Staff1692 Words à |à 7 Pagesthe global issue of mental health and shortage of nursing staff. Mental health is not the primary choice of nursing students when they graduate, and there is a shortage of psychiatric nurses as the older generation is coming closer to retirement. Across the states in Australia, studies have been conducted by Registered Nurses to survey and analyze nursing students and their field of preference after graduation. From the studies analyzed in this literature review, mental health has the least numberRead MoreThe Personality Tests On Indiana Career Explorer1118 Words à |à 5 PagesIndiana Career Explorer, the tests gave me a couple o f examples of fields I would be successful in, it told me what values may be important to me in a workplace environment. I feel these assessments were spot on and I have more confidence in my ability to be successful in my career choice. According to the Kuder Career Interests assessment, I would be very successful in the following categories: professional support services, teaching and training, counseling and mental health services, health informaticsRead MoreReflection On Mental Health802 Words à |à 4 PagesIn my opinion, mental illness is also called psychiatric disorder, which affects an individualââ¬â¢s way of thinking, behaving and perceiving, and interacting with other people. Upon reflection, I felt that my anxiety was largely due to my negative preconceptions about mental illness especially my belief that mentally ill people are violent, unpredictable, and dangerous. These views were not only a result of a lack of knowledge about mental illness but also due to the impact of negative media and culturalRead MoreNurse Manager Of The Child / Adolescent Psychiatric Units At Kingswood Hospital1098 Words à |à 5 PagesNursing jobs provide emotionally and financially rewarding careers. The health care indu stry employs millions of nurses and the job outlook continues to improve each year. This paper explores two common types of degrees held by Registered Nurses (RN) and seeks to emphasize the primary differences between the two. An individual who has a Bachelor of Science in Nursing (BSN) or an Associate Degree in Nursing (ADN) can become an RN after passing the NCLEX-RN examination. However, there are certain advantagesRead MoreNursing Philosophy1373 Words à |à 6 PagesNursing Philosophy Ayesha Muhammad Alcorn State University July 27, 2010 Nursing Philosophy Nursing is more than just simply a career. Nursing is a calling from a higher power. I chose to be a nurse for several different reasons. My uncle was diagnosed with terminal lung cancer in (date). The care and compassion shown to my uncle put nursing in another perspective for me. The feelings of care and comfort my family received during this tragic time had a strong impact on my decision toRead MoreNursing a Successful Career Essay1013 Words à |à 5 PagesRegistered nursing is among the top 10 occupations with the largest job growthââ¬â¢Ã¢â¬â¢ according to The Bureau of Statistics but why? Registered nursing is all over the world. In every hospital you will find many registered nurses because it is a good career to get into. A job industry that will never run out of jobs is the heath industry because everyone in the world needs health care treatment. Students should look into healthcare careers id they want a successful life and career. Registered nursing needRead M oreMy Goal And Future As A Psychiatric And Mental Health Nurse Practitioner1399 Words à |à 6 Pagesskills thought to me by the diverse professors and student. Being a nurse for 9 years with a diverse background has provided me with some experience and eagerness to achieve evidence base practice to advance my knowledge as a Psychiatric and Mental Health Nurse Practitioner (PMHNP). The purpose of this paper is to guide me through this learning process to stay focus on my goal and future as I advance in the learning process. Education and professional background My educational background is theRead MoreMental Health : An Essential Part Of Health825 Words à |à 4 PagesIntroduction Mental health is considered as an essential part of health in which an individual recognizes their full capacity to deal with pressures that surround them, work productively and be of positive influence to society. World Health Organization [WHO] (2008) reported that Australia contributes an estimate of 29.4% of neuropsychiatric on the global burden of disease. In 2015 the revised Australian Nursing and Midwifery Federation [ANMF] Policy states that the distribution of health care in mentalRead MoreThe Personal Philosophy Of Nursing1642 Words à |à 7 Pagespaper is aimed at addressing the personal philosophy of nursing (PPN) in caring for the people, their-health and their-environment. PPN is defined as the way of navigating true about understanding individual or people living situation in according to their values, beliefs, health and surrounding (Whitman, Rose, 2003). This PPN has reflected many times in my previous works as an assistant in nurse, with the ACT agents known as Ru bies Nursing. In this role, I have cared for both moderate and highlyRead MoreReflection, Challenges, And Ideas1287 Words à |à 6 PagesReflection, challenges and ideas to explore Zak wishes to pursue postsecondary education and has definite career goals, just like many other young adults. Unfortunately, he is up against many barriers such as poverty, homelessness, mental illness and lack of social support, and our system has fallen short in addressing those barriers and in making higher education easily accessible to him. Young adults go through many life transitions and experiencing a FEP add greatly to the complexity of this
Wednesday, May 6, 2020
Resistance of bacterial to antimicrobial agents Free Essays
Introduction Bacterial resistance to antibiotics is a global problem in the treatment of bacterial infection. Bacterial resistance is a mechanism by which bacterial are able to overcome antibiotic meant to destroy or kill them, these bacterial multiply to cause disease in humans figure 1 (Patrick, 2003) Figure1 the non antimicrobial resistance and non antimicrobial resistance Although the most resistant bacterium can be inhibited or destroyed by using a high concentration of antibiotic, subjects on the other hand may not be able to bear the high concentration of antibacterial agents that may be required treat some bacterial infection or disease. Bacterial species differ in their susceptibility to an antibiotic or antibiotics. We will write a custom essay sample on Resistance of bacterial to antimicrobial agents or any similar topic only for you Order Now For instance some strains of Streptococcus pneumonia in Britain are inhibited by 0.01mg/l of benzyl penicillin thus the minimum inhibitory concentration, and that of Escherichia coli, a dose 32-64mg/l is needed to inhibit the growth or kill the bacterial but this becomes highly toxic to the human body cannot manage. This opens the view of clinical resistance, which is based on the on effect antibiotics on humans and misuse of antibiotics. Clinical resistance is therefore a process by which the type of infecting pathogenic bacterium, its point of attachment in the body, the distribution of antimicrobial in the body, its concentration at site of infection and the immune status of the subject interact(Gerard,2011). Bacterium uses enzymes, efflux pump, gene, helix ring as well as plasmid to defend itself or to develop resistant to antibiotics. (figure2) Figure 2 structure of a resistant bacterium Beta- lactamase Beta-lactams are of copies penicillin, a large group of antibiotics that are made up of all the antibiotic agents with a four ring in their molecular structure. The bacterial cell wall serves as a protective tool for the bacterial against any foreign substances such as antibacterial agents, from entering inside the bacterial to destroy its internal protective structures. The beta-lactam antibiotic works by blocking the cell wall synthesis of the bacterial. Douglas (2002), but bacterial develop resistance to beta lactam by attacking the four ring structure shown in blue in figure of the beta-lactam through an enzymatic reactions (figure1). Bacterial produce beta lactamase enzyme to breaks the beta-lactam ring of the antibiotic and makes the antibiotic ineffective to block the bacterial cell wall synthesis and hence a resistance to the antibiotic (Miller et al., 2004). Figure3 structure of beta-lactam (www.users.rcn.com/jkimball.ma.ultranet/Biology/pages/A/Antibiotics) Mutation at the target sites Some antibiotics such as Streptomycin inhibits bacterial protein synthesis by binding to the 16SrRNA and blocks the function of the ribosome but bacterial changes the 16SrRNA gene and limit the attraction of streptomycin to the 16S molecule bacterial mutate and acquire a new DNA. In imipenem resistant, Pseudomonosa aerugeninosa, lack the specific D2 porin and imipenem cannot break through the cell. Changing the main site of action may change the drug target in that antibiotic may enter the cell but may miss the target and may not be able to bind, the antibiotic may not be metabolised. This makes the antibiotic inactive in the bacteria and as result the bacterial develop tolerance (Springer et al., 2001). Enzymatic modification Ciprofloxacin act together with an enzyme gyrase to block its enzymatic action. An alteration in each the gene that is gyraseA or gyraseB would change the molecular arrangement of the gyrase and as such limit the binding affinity of the enzyme for ciprofloxacin. It therefore prevents the antibiotic from blocking the gyrase and this process enables the bacteria cell more resistant to the antibiotic (ciprofloxacin) (Gerard, 2005) Efflux of antibiotics from the cell by pump Other bacterial such as the Escherichia coli create a multiple antibiotic resistance (MAR) outflow pump gives the bacterial with resistance to antibiotics such as tetracycline, erythromycin or nalidic acid. The pump drives out the antibiotic from the cytoplasm of the bacterial cell and allows the bacterial to maintain the intracellular levels below the toxic or lethal concentrationThe MAR pump is made of proteins MarA and MarB, whose production is blocked by the controlling protein Mar. Poole (2000) These changes get rid of the suppression control of Mar and leads to much production of the Mar A and B efflux pump. The bacterial cell wall is able to get rid of higher concentrations of antimicrobial agents and as such become resistant to the antibiotic (Cohen et al., 1988). Acquired Resistance by alternate metabolic pathways Resistance in bacteria may be acquired when a bacterium is been exposed to antibiotic for a long period of time for example vancomycin resistance in Escherichia coli. This may be by mutation or by gaining a new DNA. Plasmids are copying pieces portion of DNA, slighter than the bacteria genome which programme their transfer by copying into another bacterial strain. These bacteria may then carry and transfer resistance gene which as part of the DNA.Viruses that infects bacterial bacteriophages can pass on resistance, especially in staphylococcus, DNA is released when bacterial dead bacterial is taken up by a viable bacterial and this is possibly route for the spread of penicillin resistance in Streptococcus pneumonia. Bacterial possesses range of biochemical genetic systems for warranting the progression and diffusion of antibiotic resistance. Genes can appear by rapid transformation (Penrose, 1998). ââ¬ËSuperbugsââ¬â¢ are used to describe a bacterium or microorganism that is able to resistant more than one or more commonly used antibiotics. Bacteria resistance to antibiotics are grouped according to the type of antimicrobial agent that they resist. The most common groups are: MRSA (Staphylococcus aureus strains resistant to mithescilin ) VRE (Entrococcus species resistant to vancomycin); these type of bacteria live in the bowel and usually cause infection such as pneumonia, heart or wound in subjects with weak immune system or subjects with chronic disease such as diabetes. PRSP (Streptococcus pneumoniae strains resistant to penicillin); ESBLs (Escherichia coli and other Gram-negative bacteria resistant to cephalosporin and Monobactams) (Gerard, 2011) Treatment of superbugs MRSA is a type of Staphylococcus aureus has develops a resistant to antibacterial activity of methicillin and the other penicillins Staphylococcus aureus may cause infection in the blood or on the skin disease such. Vancomycin is a glycopeptide that is effective for the treatment of MRSA. It is hard and large molecule that blocks the last step of bacterial cell wall synthesis through hydrogen bonds with D-alanyl-D-alamine end of the peptodoglycan (PDG) side chains(Reynolds,1989)). Subjects infected with MRSA are treated with vancomycin but very painful through the intramuscular route and a rapid administration into the veins may cause an allergic reaction called the red-man syndrome, therefore a slow infusion of 50mk/kg is given two times daily for 7 days. Daptomycin is a broad spectrum antibiotic that has been approved by the American food and drug Administration for the treatment of MRSA, VRE and PSBP. It binds irreversibly to the bacteria cell membrane and depolarise it and m ore Potassium ions move out of the cell to create an inbalance of the ion-concentration gradient. Currently, Daptomycin shows no cross-resistance. A dose of 4-6mg/kg is administered once daily for 7 days. It is not metabolised in the liver. Daptomycin interacts with the HMG-6A reductase inhibitors such as statin. Nausea, constipation and headache are the main side effects associated with the use of Daptomycin. Quinupristin was well used in the year 2000 for the treatment of hospital acquired infection. Quinupristin main function was to interfere with both the early and the last phase of bacterial protein synthesis but the major problem was that it has to required slow infusion for a large volume fluid just as vancomycin and as such could only be used for inpatients subjects(Despoina and Jordi,2006)). Dancer, an oral Streptogramin has been was developed and out 53 subjects 39 were successfully cured of MRSA infection. A new glycopeptide, MDL63246 with a similar mechanism of action and pharmacokinetics as vancomycin is under early stages of development and would be more effective at lower dosages than vancomycin and less side effects. (Franz-Joseph and Mark, 1997) A new approach for VRE treatment is the blocking of oxazoliddines from flowing out of the bacterial cell and broad spectrum pumps of Gram negative bacterial is being studied for future treatment of VRE. (Livermore, 2003).Linezolid belongs to the oxazolinones class of antibiotics and it binds to the 50S ribosomal segment and blocks bacterial protein synthesis. can be administered intravenously or orally .Through the oral administration, a subject is given 600mg two times daily for 10-14 days and 600mg 30-120 minutes twice daily for one week for intravenous route. Moxifloxacin is a drug of choice for the treatment of PRSP It work by inhibiting DNA synthesis by enhancing cleavage of DNA of the bacterial DNA enzyme complex of the DNA gyrase and type IV topoisomerase figure. The dose regime is based on the type of infection, for the treatment of acute bacterial sinusitis a 400mg of Moxifloxacin is given daily for 10 days and 400mg daily dose of Moxifloxacin for 7-14 days is used treat community acquired pneumonia by Streptococcus sp. Figure3 the mechanism of action of Fluoroquinolones (www.mecriticalcare,net/downloads/Dcourse/AntimicrobialAgents Tigecycline is currently used to treat ESBPLs treat Gram negative enteric rod such as E. coli and Gram negative bacilli such as the Pseudomonas spp. Tigecycline interfere with the bacterial protein synthesis by attaching to the 30S of the ribosomal subunit and this 100mg load dose is given initially and 50mg subsequent dose of every 12 hours is administered for seven days (figure3). (Wunderink et al., 2003) Figure3 Tigecycline binding to Ribosome 30S subunit at:www.mecritcalcare.net/AntimicrobialAgent. Conclusion Bacteria or microbes are constantly reproducing at a faster and becoming resistant to antimicrobial agents. Antimicrobial resistance is a global crisis new and more potent antibiotics would have to be developed to overcome the problem of antibiotic resistance. Identification of natural products and knowing their biosynthesis from the bacterial source would enable scientist to find well defined antibiotic structures to that could kill or destroy all kinds of bacterial. Scientist may target ribose DNA, RNA or the peptodoglycan. Reference Brumfit, W.and Hamilton-Miller, J. (1989) Methicilin-resistant Staphylococcus aureus. N Eng J Med 320:1188-1196 Cohen, S.P., McMurry, L.M. and Levy, S.B. (1988) marA locus causes decreased expression of OmpF porin in multiple-antibiotic-resistant (Mar) mutants of Escherichia coli. Journal of Bacteriology 170:5416-5422 Despoina, K.and Jordi, R. (2006) Hospital ââ¬âacquired pneumonia in the 21st century: a review of existing treatment options and their impact on patient care. Expert Opin.Pharmacother 7 12) 1555-1569 Douglas, N.F. (2002) Extended-Interval Dosing of Aminoglycoside Antibiotics in critically ill patients. Journal of Pharmacy Practice15:85-95 Franz-Joseph, S.and Mark, E.J. (1997) Antibiotics for treatment of infections caused by MRSA and elimination of MRSA carriage: What are the choicesInternational Journal of Antimicrobial Agents 9:1-19 Gerald, D.W. (2005) Bacterial resistance to antibiotics: Enzymatic degradation and of modification. Advance Drug Delivery Reviews 57:1451-1470 Gerald, D.W. (2011) Molecular mechanism of antibiotic resistance. Chem.Commun. 47:4055-4061 Livermore, D.M. (2003) Linezolid in vitro mechanism and Antimicrobial spectrum. Journal of Antimicrobial chemotherapy 51:9-16 Miller,C.,Thomsen,C.G.,Mosseri,H.I. and Cohen,S.N.(2004) SOS response induction by ?-lactams and bacterial defence against antibiotic lethality. Science 305:1629-1631 Patrick, F.M.D (2003) Antimicrobials: Modes of Action and mechanism of resistance. International Journal of Toxicology 22:135-143 Penrose, E. (1998) Bacterial resistance to antibiotics-a case of unnatural selection. Creation research Society Quarterly 35:76-83 Peter, N.B. and Morris, J.B (2008) Clinical Pharmacology.edn 10.Churchil Livinstone.london Poole, K.(2000) Efflux-mediated resistance to Floroquinolones in-gram-negative bacteria. Antimicrobial Agents and Chemotherapy 44:2877-3884 Reynolds, P.E. (1989) Structure, biochemistry and mechanism of action of glycopeptide antibiotics.EurJ.clin Micr infection.Dis 8:943-950 SpringerB.,Kidan,Y.P.,Prammananan,K.E.,Bottger,E.C. and Sander,P.(2001) Mechanism of streptomycin resistance: selection of mutation in the 16S rRNA gene conferring resistance . Antimicrobial Agents and Chemotherapy 45:2877-2884 ww w.web-books.com/MoBio/free/ch8A.htm www.mecriticalcare,net/downloads/Dcourse/AntimicrobialAgents www.users.rcn.com/jkimball.ma.ultranet/Biology/Pages/A/Antibiotic How to cite Resistance of bacterial to antimicrobial agents, Essay examples
Tuesday, April 28, 2020
Marketing Plan Legacy Village
Introduction Marketing plan is essential for companies or enterprises in order to reach their clients and establish a strong base of customers. It describes the strategies, which an organization intends to use to retain and attract customers (Berkowitz 127). Therefore, marketing plan is significant for success of an organization.Advertising We will write a custom essay sample on Marketing Plan: Legacy Village specifically for you for only $16.05 $11/page Learn More It is therefore, paramount for organizations to develop effective marketing plan. This helps in management and operational plans for the organization. In addition, marketing plan assists organization to accomplish the set goal. This report devises budget of one of products of Legacy Village and evaluates outcomes to measure the effectiveness of marketing plan. Legacy Village is located in Layton. It a serene and convenient place that offers services such as retirement living, assisted living, rehabilitation, and memory care. Retirement living enables clients to interact with each other comfortably through learning and leisure activities. Assisted living entails providing services for senior people who are unable to manage themselves. However, these people do not require comprehensive and intensive daily medical care. Memory care encompasses total management and assistance of senior people. Professionals in memory care help clients in grooming, bathing, and eating. Finally, rehabilitation at Legacy Village offers services such as recovery from surgical operations, strokes, injuries, or orthopedic cases of hospitalization (Legacy Village 1). Legacy Village is extremely essential for helping seniors who have some disabilities as well as those in the recovery process. It is therefore significant for this organization to develop a marketing plan that enables it to achieve its goals. The following table indicates budget estimates for the retirement living. This is one of the p roducts, which Legacy Village offers to its esteemed customers. The budget shows the costs of services such as an advertisement in both print and electronic media. Table of Cost Estimates for Retirement Living at Legacy Village of Layton Type of Advertisement Cost Estimate (U.S Dollars) Daily Newspapers $2000 Television $1500 Online $2000 Social Media $3000 Exhibitions $5000 Publications/Articles/Brochures $8000 Telemarketing $2500 Grand Total $26000 Methods to Evaluate outcomes of Marketing Plan on Retirement Living It is highly prudent for Legacy Village to devise a method that evaluates the outcome of the marketing plan for retirement living. This is because evaluation of the plan is tremendously significant in establishing whether the organization has accomplished its set goals and objectives (Berkowitz 200). This therefore means that the marketing plan should give tangible results for the success of Legacy Village. Some of the ways that the health organiza tion in question can use include, bottom up approach, negotiated approach, and objectives approach.Advertising Looking for essay on business economics? Let's see if we can help you! Get your first paper with 15% OFF Learn More Bottom-up approach entails getting feedback from the consumers of the retirement living service. This will help the management at Legacy Village to have deeper knowledge of the demands of their customers. On top of this, organization will improve the quality of its services hence satisfaction to the customers. Negotiated approach is a method that encompasses collecting comments from a big number of people. This will assist Legacy Village elicit and attract potential customers to use their products. This organization can create a strong database, which will enable current and potential customers to post their feedback. A third method, which is sound for evaluation entails objective approach. The organization in question can use statistical data s uch as records and surveys (Berkowitz 195). This therefore calls the organization to keep the data of any transaction and activities safely. The three ways of evaluation, which this report has highlighted can benefit the Legacy Village in their mission to care for seniors. Work Cited Berkowitz, Eric. Essentials of Health Care Marketing. New York: Aspen publishers, 2011. Print. Legacy Village. Legacy Village, Layton. Web. https://www.legacyretire.com/ This essay on Marketing Plan: Legacy Village was written and submitted by user Kaitlynn Lynn to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.
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